Thursday, August 27, 2020

The Reader Essay Example For Students

The Reader Essay Memory is an influential idea. Frequently when an individual experiences a horrendous circumstance, the implications of these activities saturate an individualfs mind unwittingly. As a result this goes through memory and becomes sub-intentionally covered inside a personfs standards of conduct for the most part. The Reader by Bernhard Schlink investigates the idea of a youthful keeps an eye on subliminal want for a lady whom he gcanft recollect to forgeth (1Memento) as she is so profoundly decorated inside his spirit. Widely praised as gA officially wonderful, upsetting, lastly ethically annihilating novel. From the first pagec it entraps both heart and mindh ( Los Angeles Times), the novel recounts to the tale of a little youngster, 15, Michael Berg, through his own inside portrayal. He gets himself sincerely and explicitly connected to a lady of over twice his age, Hanna Schmitz. She at that point makes him extremely upset by abandoning him. Michael is genuinely torn by this occurrence and thusly builds up a subliminal fixation on her. We will compose a custom exposition on The Reader explicitly for you for just $16.38 $13.9/page Request now A long time after the puzzling vanishing of Hanna, Michael weds a lady named Gertrude. gGertrude was savvy, proficient, and loyalh (3p 171) yet she never satisfied Michael similarly as Hanna had beforehand. Unconsciously he drove her away through his steady examinations and disappointment that Gertrude couldn't be the lady he needed. gI would compare constantly the manner in which it was with Gertrude and the manner in which it had been with Hanna; over and over, Gertrude and I would hold one another, and I would feel that something wasn't right, that she wasn't right, that she moved wrong and felt wrong, smelled wrong and tasted wrong.h (p 171) In his relationship with Gertrude, Michael can't make sure to overlook Hanna as, at that point, he doesnft acknowledge yet subliminally he is looking at the two and attacking his relationship. In the oblivious state, dreams are the most flawless type of truth into a personfs subliminal. In Michaelfs dreams he truly longs for Hannafs nearness. gIt took some time before my body quit longing for hers; occasionally I myself knew about my arms and legs grabbing for her in my rest, and my sibling announced more than once at table that I called out eHannaf in the nighth (p 85). The powerless idea of Michaels activities show the amount Hanna has influenced his inner mind and despite the fact that he is made mindful of his activities, his physical reliance originates from the profound startling inside him. On another event, after Hannafs passing, it is reported that Michael by and by subliminally wants her quality. Michael longs for Hanna while making a trip through the wide open to offer Hannafs last wishes. gI longed for Hanna and myself in a house in the harvest time bursted slopes that were coating our course. Hanna was more seasoned than when I had met her and more youthful th an when I had met her once more, more established than me, more alluring than in prior years, increasingly loose in her developments with age, more at home in her own body. I saw her escaping the vehicle and getting shopping sacks, saw her experiencing the nursery into the house, saw her set down the packs and venture out in front of me. My aching for Hanna turned out to be solid to such an extent that it hurt. I battled against the yearning, contended that it conflicted with Hannafs and my world, the truth of our ages, the truth of our circumstancesh. The inside portrayal here permits the concentration to hold a scrutinizing and reflective perspective on Michaels thought designs. He recalls his fantasies and notes them as being unreasonable and bizarre of the real world, yet he winds up longing for her still. Hanna has had such an effect on Michaels passionate memory that, as much as Michael attempts to consume his brain so as to overlook her, he simply cant. Hanna is imbedded into his mind and in this way rendering him totally feeble to her powerful power that rises inside him, subliminally. .u5a6f2609f865faf7628ac51502c5e86b , .u5a6f2609f865faf7628ac51502c5e86b .postImageUrl , .u5a6f2609f865faf7628ac51502c5e86b .focused content region { min-tallness: 80px; position: relative; } .u5a6f2609f865faf7628ac51502c5e86b , .u5a6f2609f865faf7628ac51502c5e86b:hover , .u5a6f2609f865faf7628ac51502c5e86b:visited , .u5a6f2609f865faf7628ac51502c5e86b:active { border:0!important; } .u5a6f2609f865faf7628ac51502c5e86b .clearfix:after { content: ; show: table; clear: both; } .u5a6f2609f865faf7628ac51502c5e86b { show: square; change: foundation shading 250ms; webkit-progress: foundation shading 250ms; width: 100%; obscurity: 1; change: haziness 250ms; webkit-progress: murkiness 250ms; foundation shading: #95A5A6; } .u5a6f2609f865faf7628ac51502c5e86b:active , .u5a6f2609f865faf7628ac51502c5e86b:hover { mistiness: 1; change: darkness 250ms; webkit-change: darkness 250ms; foundation shading: #2C3E50; } .u5a6f2609f865faf7628ac51502c5e86b .focused content territory { width: 100%; position: relati ve; } .u5a6f2609f865faf7628ac51502c5e86b .ctaText { fringe base: 0 strong #fff; shading: #2980B9; text dimension: 16px; textual style weight: intense; edge: 0; cushioning: 0; text-beautification: underline; } .u5a6f2609f865faf7628ac51502c5e86b .postTitle { shading: #FFFFFF; text dimension: 16px; textual style weight: 600; edge: 0; cushioning: 0; width: 100%; } .u5a6f2609f865faf7628ac51502c5e86b .ctaButton { foundation shading: #7F8C8D!important; shading: #2980B9; outskirt: none; fringe span: 3px; box-shadow: none; text dimension: 14px; textual style weight: striking; line-stature: 26px; moz-fringe sweep: 3px; text-adjust: focus; text-adornment: none; text-shadow: none; width: 80px; min-stature: 80px; foundation: url(https://artscolumbia.org/wp-content/modules/intelly-related-posts/resources/pictures/basic arrow.png)no-rehash; position: outright; right: 0; top: 0; } .u5a6f2609f865faf7628ac51502c5e86b:hover .ctaButton { foundation shading: #34495E!important; } .u5a6f2609f865faf7628ac5 1502c5e86b .focused content { show: table; stature: 80px; cushioning left: 18px; top: 0; } .u5a6f2609f865faf7628ac51502c5e86b-content { show: table-cell; edge: 0; cushioning: 0; cushioning right: 108px; position: relative; vertical-adjust: center; width: 100%; } .u5a6f2609f865faf7628ac51502c5e86b:after { content: ; show: square; clear: both; } READ: Physics Persuasive EssayAnother issue created inside the novel is the possibility of the effect of the war with the German culture. The individuals of Germany can't figure out how to overlook the terrible activities that happened during WWII, likewise with Michaels connect to Hanna, in light of the fact that the occasions were shocking to such an extent that they are engraved on the inner mind psyches of each citizen. They attempt to overlook the past yet their goals are obstructed by the intensity of their recollections and the influence they have had on them intellectually and now and then genuinely. A case of this in the novel is Hann afs putrefying blame about her brutal and deceptive acts towards the Jewish ladies and youngsters that were in her consideration. The peak of the novel sees Hannafs distress to free herself from these recollections as she ends it all. Prior to her demise, Hanna addresses Michael about the waiting spirits of the dead that frequent her spirit, gThey came each night, regardless of whether I needed them or noth (p 197). Hanna acknowledges her transgressions and looks for absolution from the spirits of those whom she acted so unfairly towards yet they don't allow her, her desire and don't disregard her. They come each night, similarly as the recollections subliminally dwell inside her brain, never to leave. Hanna can't make sure to overlook the awful recollections of her encounters during the 1940fs in light of the fact that they have become a piece of her inner mind.

Saturday, August 22, 2020

The Harlem Renaissance John Birks Gillespie and Selma Burke free essay sample

The Harlem Renaissance was a period of incredible achievements among African Americans. Mary gems, verse, and music during this time got striking even to today. Two rousing individuals of this timespan were John Barks Gillespie and Selma Burke. John Barks Dizzy Gillespie was conceived on October 21, 1917 in Cherry, South Carolina. He was the most youthful of nine youngsters. His dad, James Gillespie, was a bricklayer and an artist as an afterthought. His mom, Little Pope Gillespie, was a house spouse and a full time mother.By the age of 12, Gillespie had involvement with playing the IANA and wanted to some time or another Join the school band. He is a tease begun playing the trombone however changed to the trumpet since he enjoyed the sound better. His family battled with neediness after his dad kicked the bucket when he was ten. This kept him from getting his own instrument. Albeit, through his battles, he despite everything figured out how to be an extremely gifted trumpet player however just in one key. We will compose a custom paper test on The Harlem Renaissance: John Birks Gillespie and Selma Burke or on the other hand any comparable point explicitly for you Don't WasteYour Time Recruit WRITER Just 13.90/page He earned a grant to Laurelling Tech in North Carolina. He contemplated hypothesis and concordance and concluded that music would be his profession.While Gillespie was with the Frankie Fairfax band, the band head, Fats Palmer, flippantly gave Dizzy his name. Gillespie played In a few melodic gatherings Including the Teddy Hill Orchestra (1 937), the Cab Galloway Band (1939), and the Earl Hines Band (1941). He had numerous unmistakable attributes about himself that turned into his trademarks. His most famous trademarks were his expanding cheeks, improved horn, and fun character. To acquire more cash, he composed plans for different groups. Counting one of his first courses of action, Planck the Cabbage, composed for Cab Galloway. In the backtalk, with the assistance of Charlie Parker, Theologies Monk, and Kenny Clarke, Gillespie made another classification of music called bebop. From the start, numerous artists didn't take to the new type of music. Be that as it may, subsequent to playing with well known artists, including Ella Fitzgerald, Duke Elongating, and some more, Gillespie established his own band in 1945. In 1947 Gillespie made melodies combined with bebop and Afro-Cuban rhythms. A portion of these melodies become successes, similar to the tune Cuban Be, Cuban Bop. Gillespie band made Its official presentation at Carnegie Hall In September of 1947 (Smith, 459).He kept on refining bebop and in 1956 the U. S. Division of State requested that Gillespie speak to the nation and take a band on a voyage through Europe, Africa, and the Middle East (Smith, 459). Gillespie kept creation music and performing up to 300 shows per year. In 1988 his new band recorded Dizzy Gillespie and the assembled Nations symphony: Live at Royal Festival Hall in London which won a Grammar Award in 1 991 . He won two additional Grammas before that in 1975 and 1980. In IEEE was regarded with a year-long precious stone Jubilee for his 50 years of execution and his 75th birthday celebration (Smith, 460).He performed for four presidents and won the renowned Kennedy Center Award. Gillespie likewise composed a life account called To Be Or Not to Bob Memoirs distributed 1 OFF associated with his stunning ability and extraordinary character by all whom he adored and motivated. Another remarkable African American during this time was Selma burke, a rousing craftsman and stone worker. Selma Hornets Burke was conceived on December 31, 1900 in Impressible, North Carolina. She was one of ten offspring of Neal and Mary Jackson Burke. Her affection for workmanship began when she was very young.Her father was a clergyman that ventured to the far corners of the planet and when hed return from abroad he would carry customary artistic work protests alongside him. Burke additionally had two uncles who likewise made a trip for the most part to Africa. They brought back loads of customary strict African figures and veils which were given to the Burkes after their demises. Along these lines, African craftsmanship was one of Salaams first references to workmanship (Whine, 191). Burke went to the main dark primary school in the Washington, D. C. Region. Sadly, the school offered no consolation for the arts.She, rather, was mother educated by William Arial, a white man who likewise empowered her affection for workmanship. She later went to Winston-Salem High School and her mom encouraged her to get handy instruction. So she went to SST. Agnes School of Nursing and turned into an enrolled nurture in 1924. In the wake of moving and proceeding with her instruction in nursing, Burke wedded Duran Woodward who eleven months after the fact, passed on of blood harming. She turned into an individual attendant for a well off Otis Elevator beneficiary and was basically unaffected by the Great Depression.Burke moved to New York in 1935 and took on a demonstrating Job and co-composed the Liberator with Claude McKay. In 1938, she went through a year in Europe finding out about various methods and expressions. After that she sought after an expert degree in form at Columbia University. She graduated with a M. F. A. In 1941 and even got an opportunity to give her work at the McMillan Galleries in New York City. Be that as it may, during World War II, Burke Joined the Ana however was hospitalized after a back physical issue. She later entered an opposition to make a profile picture of President Franklin D. Roosevelt in 1944.She had various private sit-downs with the president himself to get the irregularity Just right. She needed this to be the best bit of figure I had ever done (Whine, 192). She made a 36 by 26 bronze plaque in profile with the four opportunities recorded along the top. It was placed in the Recorder of Deeds Building in Washington, D. C. The plaque was uncovered by Frederick Weaver on September 24, 1945. John R. Meeting, the man who structured Roosevelt profile on the dime, use Salaams plaque as a primary reference. Burke instructed at numerous schools for a mind-blowing duration. She even got remarried and moved to Pennsylvania.

The role of the health and social care worker Essay Example for Free

The job of the wellbeing and social consideration laborer Essay A working relationship is not the same as an individual relationship in light of the fact that a working relationship is progressively proficient; there are limits, explicit targets and purposes. There are proficient implicit rules, boss arrangements and systems likewise there are time constrains and being sometimes cone way relationship. The three arrangements for whom I work with and there work jobs are movement staff, care staff and music treatment staff. I speak with these montages and work together to build up and keep up the trust and certainty of administration clients and care staff. I additionally have a decent discussing relationship with these. Giving the arrangements; and techniques and conveying in organization. It is essential to work in organization together in the medicinal services to accomplish the best results for the people and its additionally significant in light of the fact that montages have all unique working abilities, information and moves, Partnership likewise to share conversations and making data connection in like manner concern. Assignment B Reflective record I was with a montage in work with an individual from care staff. I was going to derrick and move a help client, utilizing a crane. My montage needed to go on break, and had a thought that would be faster than utilizing a derrick and utilizing the right technique properly and securely. My arrangement needed to lift the administration client up from that point wheelchair and move them onto a bed, yet I was absolutely against this. I didn't consider, to utilize this kind of technique for move, as I felt that I would harm, myself, the administration client and my collection. Also, hazard the chance of loosing my activity and loosing someone’s life. This occurrence included clash between my working composition since I would not like to proceed with it, and work in a hazardous way. I went to my line supervisor and said about this circumstance. I needed to report this by filling in an occurrence structure. I didn't get the help at the ideal time, as my trough was absent. I believe that I managed this episode compelling and expertly and keep up a decent degree of care to the administration client. I could have reacted distinctively by not being proficient and keeping my working relationship, yet I needed to in light of the fact that this was a business related occurrence.

Friday, August 21, 2020

Sports Injury Essay Research Paper POLICY PAPER free essay sample

Sports Injury Essay, Research Paper Arrangement PAPER: SPORTS INJURY The ICCWA takes note of that: 1. Sports harms in Australia are assessed at 1 million for every twelvemonth. Around 200,000 of these are viewed as genuine and 40,000 require hospitalization or careful intervention ( CHPR, 1990 ) . 2. There is an insufficiency of normalized informations on athleticss harms in Australia, both when all is said in done, inside highlighting codifications and for schools ( CHPR, 1992 ) . This insufficiency of data is a hindrance to injury bar. 3. The immediate clinical expense of athleticss harms in Australia in 1987-88 was evaluated at between $ 333-400 million. A more distant assessed $ 400 million was lost through work truancy. Give 1990 cash esteems, whole 1990 expenses are evaluated at $ 1 billion ( CHPR, 1990 ) . 4. It is evaluated that between 30-50 % of all damages might be forestalled ( CHPR, 1990 ) . 5. The best possibilities for hurt bar exist in guidance and guideline change. Mentor, coach, educator, member, chie f and umpire/ref guidance and the ensuing improvements in member preparing could essentially chop down the frequency of many highlighting harms. We will compose a custom paper test on Sports Injury Essay Research Paper POLICY PAPER or on the other hand any comparable point explicitly for you Don't WasteYour Time Recruit WRITER Just 13.90/page Changes to guidelines, their requirement and the chaperon disciplines for infringement could other than chop down the frequency of some highlighting harms. 6. It is assessed that a general spending of $ 0.5 million in bar outgo more than three mature ages could warily result in a potential one-year cost economy of up to $ 200 million ( CHPR, 1990 ) . 7. The Australian Sports Medicine Federation ( ASMF ) conducts a national athleticss harms bar programmme. This program comprises of the National Sports Trainers Scheme # 8211 ; NSTS ( Sports Medicine Awareness Course - SMAC, Level 1 and Level 2 Sports Trainers Courses ) and the Guidelines for Safety in Children # 8217 ; s Sport. 8. The Australian Physiotherapy Associaton ( WA Branch ) has started Sports Injury Prevention Programs focused on explicit local gatherings. 9. The NSTS plays an of import work in teaching Sports Trainers for their parts to highlight wellbeing in the Australian games framework. 10. Albeit hard to precisely figur e, the technique is viewed as answerable for a major abatement in clinical, cultural and individual expenses of athleticss hurt ( CHPR, 1992 ) . 11. The full advantage of bing and future athleticss hurt bar projects can be upgraded by more noteworthy handiness and network course to these projects. An expansion in subsidizing for program improvement and exposure is expected to better network dish to these programmmes. The ICCWA accepts that : 12. Avoidance of injury is the most significant type of injury the executives. 13. Injury avoidance instruction of sports members, sports mentors, mentors, educators, guardians and managers is a key factor in injury counteraction. This training is important to achieve enhancements in player planning, rule adjustment and office improvement. 14. Sports Injury Prevention Programmmes ought to be accessible to all school understudies: essential, lower optional and upper auxiliary. 15. Given fitting financing, a huge increment in the present degree of individuals qualified at SMAC and Sports Trainer level in the Australian game framework is conceivable. 16. There is a huge requirement for ordinary normalized assortment of information on sports wounds in Western Australia, both when all is said in done, inside explicit codes and inside schools. 17. The National Sports Trainers Scheme can possibly add to the assortment of sports injury information in WA. 18. Sports wounds can be forestalle d by the utilization of Australian Standards defensive hardware, eg. eye-watches for those playing squash and indoor cricket; and that such hardware ought to be not dependent upon the 20% deals charge. The ICCWA suggests that: 19. All schools and wearing affiliations be urged to make injury avoidance instruction compulsory for all educators, mentors and coaches associated with sport. 20. ICCWA Board send a duplicate of this strategy to the significant government priests (Education, and Sport Recreation), the WA Sport Federation, and Tertiary Institutions engaged with educator training. 21. Bureaucratic and State Government ought to think about more noteworthy monetary help for the more extensive lead of existing and future games injury anticipation programs. 22. ICCWA explore potential plans and frameworks for the assortment of sports injury information in WA. 23. The games injury avoidance programs started by similarly invested associations be embraced and upheld by ICCWA. Referenc es: . Place for Health Promotion and Research (CHPR) (1990) Sports wounds in Australia: Causes, expenses and counteraction. A report to the National Better Health Program. Sydney: CHPR. . Place for Health Promotion and Research (CHPR) (1992) Evaluation fo the ASMF National Sports Trainer’s Scheme. Sydney: CHPR. Affirmations: ICCWA recognizes the help of Mr Kyle March, Mr D. Gurumoorthy and Mr Gavin Maisey in the planning of this strategy paper. The perspectives introduced in this paper are those just of the ICCWA. ICCWA additionally recognizes the help of the Western Australian Health Promotion Foundation (Healthway).

Blog Archive Yale SOM Essay Questions, 20132014

Blog Archive Yale SOM Essay Questions, 2013â€"2014 The Yale School of Management has released its 2013â€"2014 MBA application essay questions, moving from four essays to just two! Below are this year’s prompts and application deadlines. Be sure to revisit the mbaMission blog next week for our essay question analysis! Essay 1 What motivates your decision to pursue an MBA?  (300 words maximum) Essay 2 The Yale School of Management provides leadership education for broad-minded, rigorous, and intellectually curious students with diverse backgrounds; a distinctive integrated curriculum; connections to one of the great research universities in the world; and the broad reach of an innovative and expanding global network of top business schools. What motivates you to apply to the Yale School of Management for your MBA? What will you contribute to Yale and Yale SOM?    (450 words maximum) Deadlines: Round 1: September 25, 2013 Round 2: January 9, 2014 Round 3: April 24, 2014 Share ThisTweet News Yale University (School of Management)

Friday, June 26, 2020

The American Renaissance Transcendentalism, Romanticism and Dark Romanticism - Free Essay Example

The American Renaissance period, circa 1820-1865, announced a new sense of nationalism that focused on the expression of modernism, academic classicism, and technology. The movement developed from various American authors trying to formulate a distinctive American literature based upon the works of European literature. However, these novels, poems, and short stories that were created, made use of innate dialect, scenery, and historical figures, in order to touch base on the American issues of this time. Some of the considerable issues during this time included abolitionism and religious tolerance. With the influence of these circumstances during the American Renaissance period, Transcendentalism, Romanticism, and Dark Romanticism became to take root within the world of literature by virtue of authors like Margaret Fuller, Ralph Waldo, Herman Melville, Nathaniel Hawthorne, and Edgar Allan Poe. The academic movement, Transcendentalism, was closely associated with the American Renaissance. This development is a system of knowledge based on the idea that humans are fundamentally pleasant, that humanitys deepest verities may be created through insight rather than reason, and that all of creation is predominantly unified. Transcendentalism became prominent among scholars and ministers in advocating the expansion of a national culture and social reform. It also served as a statue to debate world issues such as abolition of slavery, workers rights, womens suffrage, and freedom of religion. The most powerful piece of literature that was published during this time period was The Dial, founded in 1840 by Margaret Fuller and Ralph Waldo. These dispatches from Italy, played a major role in precipitating the Civil War. (Fleche, Andre) This served as an assembly for the publication of fiction, essays, and poetry by several foremost American Transcendentalist and American writers. The arts and literature movement, Romanticism took place based on a cultural revolution. Romanticism incorporated the principles of imagination, individuality, and spirituality. Against the strongly misconceived conception, Romanticism was not developed by love. Instead, it has been historically affiliated with narratives full of adventure and romance that stems from myths rather than stories based on historical events. However, the stories that were published during this time period do have a sense of realism to them due to the storylines being influenced by political, social, and economic changes. Dark Romanticism is a derivative of Romanticism. The gothic, the grim, and the unpropitious are just a few words to describe this fascinating movement that took place during the 19th century. These adjectives that are continuously embraced, helped to shape this movement into what is now one of the most popular sub-genres. Life was presented in the Dark Romantics as being colorful, yet dark, structured, yet impulsive, and predictable, yet paradoxical. Unlike the Romantics, the Dark Romantics set their stories based upon the wickedness and evil that is within man. They acknowledged both the good and evil in humans. Prominent Dark Romanticism authors during this time period were Nathaniel Hawthorne, Edgar Allen Poe, and Herman Melville. Nathaniel Hawthorne is known for several of his Dark Romantics, including Young Goodman Brown, The Ministers Black Veil, and The Scarlet Letter. The short story, Young Goodman Brown, is set through the streets of Salem (Norton Anthology 347) and tells of a man that sets out in woods filled with deepening gloom (Norton Anthology 349) where he is faced with his future by seeing the shape of evil (Norton Anthology 353). This short story is set as a Dark Romantic as Hawthorne goes over all the dark, and gruesome details of Young Goodman Browns travels. Another one of Hawthornes popular Dark Romantic tales is The Ministers Black Veil, published in 1832.This tale is set within a puritan town, where the natives are made aware of their sins. It was common for Hawthorne to use references to the Salem Witch Trails, as it is so that his great-great grandfather, John Hathorne, was a judge at the trial, which Hawthorne gained a great deal of inspiration from. This only further sets the eeriness of his stories apart from other authors of Dark Romantics. Authors during Hawthornes time period gained inspiration from Hawthornes dim works of literature. One of those authors is Herman Melville. Herman Melville is known for his novel Moby Dick. Melvil le published Moby Dick, a Dark Romantic, a year after The Scarlet Letter was published, in dedication to Hawthorne (Bolton 36). Not only did Hawthornes, The Scarlet Letter, have a long effect on Melville, but it also has a long-standing inclusion in high school and college American Literature syllabi (Bolton 37). This ensures that generations to come will continue to encounter Dark Romantic novelist like Hawthorne, and Melville. Another prominent Dark Romantic author during this time period is Edgar Allan Poe. Poe had many dark short stories, one being The Fall of the House of Asher. This story tells of a family that is falling apart as their house his literally falling around them. The first line of the story includes the adjectives, dull, dark and soundless (Norton Anthology 629). These words are used to describe an Autumn day. A day that should be full of color however, Dark Romantic author, Poe described it in as any dark author would. Poe uses this story along with many other o f his stories to not only express this sub-genre in words but also within music. The Fall of the House of Usher, is used to evoke music as a figure for both diseased sympathy and madness, says Sean Kelly. There is a loose vague connection between the words and the characters, that sets the dark, gloomy tone. Hawthorne, Poe, and Melville are all very influential Dark Romantics. They were able to acknowledge the existence of pain, sin, and evil within the lives of humans, and even formed a counterpoint to the Transcendentalists. With these authors use of dark adjective and symbols, they were able to portray works of literature that are categorized as Dark Romantics, allowing the authors to play a vital role in the American Renaissance. The American Renaissance period took place from approximately 1820-1865. During this time period, Transcendentalism, Romanticism, and Dark Romanticism began to flourish. However, the three had very different views of the world. Transcendentalists believed that God is present in every aspect of nature, Romanticists believed that intuition, imagination, and emotion are superior to reason, and the Dark Romanticists believed that spiritual facts lie beneath the appearance of nature. Although all of the differ, each one has a group of literary authors, such as Margaret Fuller, Ralph Waldo, Herman Melville, Nathaniel Hawthorne, and Edgar Allan Poe, that have made a difference in the world of literature.

Monday, May 25, 2020

What Is an Aside in Speech and Writing

In conversation or drama, an aside is a short passage that is spoken in an undertone or addressed to an audience. In written form, an aside may be set off by parentheses. Examples and Observations in Literature As we went in to dinner, Mrs. Ashcroft-Fowler said in a quiet aside to her husband, Has Meadows spoken? He shook his head rather gloomily and answered, No, he has said nothing yet. I saw them exchange a glance of quiet sympathy and mutual help, like people in trouble, who love one another.(Stephen Leacock, ​Are the Rich Happy, Further Foolishness)Every Tuesday I sit down with the speaker and the majority leader to discuss the weeks agenda. Well, discuss is probably the wrong word. They talk while I sit quietly and imagine their lightly salted faces frying in a skillet.(Kevin Spacey as Frank Underwood in an aside to the audience in Chapter 2 of House of Cards, 2013)He made us a list: wed need to get some black sesame seed, a specifically sized white porcelain bowl, a bottle of 100 (or stronger)-proof alcohol, and a large, new, six-inch kitchen knife. (I swear to you Im not making this up. He may have been making it up, but Im telling you exactly what happened.)(Paul Reiser, Fam ilyhood)I admired [C.S. Lewiss] use of parenthetical statements to the reader, where he would just go talk to you. Suddenly the author would address a private aside to you, the reader. It was just you and him. Id think, Oh, my gosh, that is so cool! I want to do that! When I become an author, I want to be able to do things in parentheses.(Neil Gaiman interviewed by Hank Wagner in Prince of Stories: The Many Worlds of Neil Gaiman)Simonides: Traitor, thou liest.Pericles: Traitor!Simonides: Ay, traitor.Pericles: Even in his throat -- unless it be the king --That calls me traitor, I return the lie.Simonides: [Aside] Now, by the gods, I do applaud his courage.(William Shakespeare, Pericles, Act II, scene five)Their marriage was like some horrible play. There were only two characters, but they never addressed each other directly. They did all their speaking in asides to the audience.(Christina Bartolomeo, Cupid and Diana: A Novel)If you are slow at this point, reader, to credit what I tel l you, it will not be remarkable. For I who observed it, can barely allow myself to believe.(Dante, Inferno, Canto 25) A Long Parenthetical Aside To the inevitable question of how a City Night School teacher of English as a second language to HIV-negative Somalian women (they have to be HIV negative or they would never get in; youre forced to take a test, which means that when we all get some perspective around the year 2050 or so, some old Somalian woman is going to sue the city for forced HIV testing and be awarded another bundle. This parenthetical aside has gone on too long, and now I must start again). To the inevitable question of how a Night School teacher of English as a second language affords two downtown rents, Julie said, Well, first of all. I dont live downtown...(Darren Greer, Still Life With June)Â   Punctuating Parenthetical Asides It is possible to enclose an entire, complete sentence with a pair of parentheses, something that cannot be done with a pair of dashes. Such a sentence could stand on its own, for instance in the midst of a paragraph, as a parenthetical aside to the sentence that preceded it. Of course, this parenthetical aside must be so complete that it merits its own sentence, a fairly unusual circumstance. As in: Im on a strictly vegetarian diet. (Well, not strictly, I do eat fish from time to time.) The doctors say it will do wonders for my heart.​ The aside is a complete thought, so it cannot fit in the midst of a sentence. Thus it is given its own sentence, made possible by parentheses.(Noah Lukeman, A Dash of Style: The Art and Mastery of Punctuation)

Monday, May 18, 2020

Resolving Conflict and Disagreements

Conflict tends to be a part of our lives and all too often, is inevitable. Emotions run high when dealing with differences over the best way to deal with differences.  Dealing with conflict and disagreement effectively is half the battle and can create positive outcomes. When conflict and disagreement are handled inappropriately, the outcome can be destructive and are rarely in the best interest of either party. At the same time, all of the parties are often under a lot of pressure.  There are more and more demands put on public education without enough resources, not only monetary but also human (not enough qualified personnel) and often those resources, but physical and the time of the professionals, are stretched thin.  At the same time, with the spread of information, often misinformation, parents sometimes pressure teachers and schools to try therapies or educational strategies that are not based on data and peer-reviewed research.   The Investments of Stakeholders Parents:   Often parents have powerfully conflicting emotions.  On one hand, they are extraordinarily protective while at the same time may feel shame or guilt over their childs disabilities.  Sometimes parents conceal these feelings, even from themselves, by coming on strong.  It is sometimes easy to become defensive, rather than hearing the love, concern and perhaps even guilt that the parents are communicating.  Teachers and Para-professionals:  Good teachers seek to do what is best for their students and take pride in their effectiveness as educators.  Sometimes we become thin-skinned if we think parents or administrators are questioning either our integrity or our commitment to the student.  Relax.  Its easier said than done, but we need to reflect rather than becoming overly reactive.  Administrators:  As well as being accountable to parents and students, administrators are also accountable to superiors who are charged with protecting the interests of the school districts, which may include keeping the costs of providing services down.  That is why they are often called the Local Education Authority (LEA) in our meetings.  Some administrators, unfortunately, dont understand that investing time and attention into their staff will produce better outcomes for everyone.   Strategies for Handling Conflicts and Disagreements Differences must be resolved - it is in the best interest of the child to do so. Remember, sometimes a disagreement occurs as a direct result of a misunderstanding. Always clarify the issues at hand. Parents and school staff members must work closely together to address the issues.Pro-active means of reducing conflict include sharing positive information about the student with parents in an ongoing manner.  It is essential for both parties to realize that the goals for the child are shared goals. Both must agree that the childs interest comes first.Avoid confrontation and deal specifically with solutions to the identified issues and be prepared to offer alternatives.Always deal with the issues rather than the emotions and the people involved. Acknowledging the emotions may be a positive way to diffuse them.  Decide on what you can compromise on, effective resolution usually requires some form of compromise on both parties behalf.Be sure that your expectations are realistic and reasonable.Specify both long term and short term goals and state when a follow-up visit should occur.All parties need to commit to the recommended solutions and agree jointly.All parties must rely on ea ch other, it is, therefore, essential to work out differences and work together regardless of how sensitive the issue is.

Thursday, May 14, 2020

Swot Analysis Report - 1228 Words

Since 1994 Hilton acquired all of Bally Entertainment, making the largest gaming company in the world. In 1997 they founded an alliance with Ladbroke Group PLC in (now Hilton Group, owner of Hilton International and the rights to the Hilton name outside the US) to unify the Hilton brand worldwide. With a downturn in the gaming industry translating into sluggish results in Hilton’s gaming segment, the company spun off its gaming interests as Park Place Entertainment. In 1999 Hilton made a massive acquisition with the $3.7 billion purchase of Promus Hotel Corp. The following year Hilton sold its flamingo Casino-Kansas City, a remaining casino property left over from the Park Place spin off, to Isle of Capri Casinos for $33.5 million.†¦show more content†¦These hotels are owned by joint ventures of which the Company owns a minority or non-controlling interest. The Company has a right of first refusal to purchase additional equity interests in certain of these join t ventures. Managing and Franchising Operations: The Company managed 210 hotels, representing 53,776 rooms, which are wholly owned by others. Under the standard management agreement, the Company operates a hotel for the benefits of its owner, which either owner or leases the hotel and the associated personal property. The Company’s management fee is generally based on a percentage of each hotel’s gross revenue plus, in the majority of properties, an incentive fee based on operating performance. The Company franchised 1,612 hotels, representing 214,824 rooms, which are owned and operated by third parties. In general. Franchisees pay the Company an initial fee based on the number of rooms in a franchise hotel and a continuing fee based on a percentage of the hotel’s rooms revenue, which may be up to 5% of rooms revenue depending on the brand. Although HHC does not directly participate in the management of operation of franchise hotels, the Company conducts periodic inspe ctions to ensure that is standards are maintained and render advice with respect of hotel operations. Timeshare Operations: Hilton Grand Vacations Company and its related entities (HGVC), which the Company wholly owns, currently manages 18Show MoreRelatedLufthansa Cargo1170 Words   |  5 PagesBrochure More information from http://www.researchandmarkets.com/reports/1322865/ Lufthansa Cargo AG - Strategic SWOT Analysis Review Description: Lufthansa Cargo AG - Strategic SWOT Analysis Review Summary Lufthansa Cargo AG(Lufthansa Cargo) is a Germany-based company which provides cargo airline, air freight and logistics services. The company is engaaged in transporting cargo and mail from airport-to-airport. Lufthansa Cargo AG has a strategic partnership agreement with Fraport AG. The airlineRead MoreMarketing Planning Of H M986 Words   |  4 PagesFor Organisational Audit The Auditing team monitors HM financial reporting which includes monitoring the effectiveness of HM internal control along with management. The organisational work for HM includes handling auditing issues and financial reports published by HM The Auditing team constantly receives information with supporting documentation for decision-making from HM involving the Managing Directors with the company’s external auditors A further task of the Auditing team is to coverRead MoreRecommending a Marketing Mix for a Product or Service1604 Words   |  7 PagesRecommending a Marketing Mix for a Product or Service Executive Summary This report mainly talked about a product-Pepsi. In this report, the purpose was compared and contrasted which 4Ps is better to the Pepsi and wanted more people to buy it. The thesis was compare and contrasts the Pepsi with the competitor - Coca Cola. So the report needed find some information and interview some people. The key finding was that SWOT and 4Ps is very important to the product. And the key conclusion and recommendationRead MoreThe Internal And External Forces That Influence Success927 Words   |  4 PagesSWOT Analysis NPO leaders and boards of directors must understand the internal and external forces that influence success. One standard tool for understanding and positioning the organization for overall improvement is the Strengths, Weaknesses, Opportunities and Threats (SWOT) analysis. (NCU, 2016) According to Weese (2009), a SWOT analysis is an honest evaluation of the strengths, weaknesses, opportunities, and threats inherent in a given situation (Weese, 2009, p. 265). It involves specify theRead MoreInformation Gathering for Business Analysis1121 Words   |  5 Pagescompany’s annual reports, newspaper, internet etc to make my analysis more comprehensive I used the following secondary sources to gather my information which enabled me to get the broad view of Lucky Cement’s Business and it helped me to make a better analysis of Lucky Cement’s Performance. Annual Reports and Books Lucky Cement’s annual reports for years 2008-2010 provided me with a bulk of information which I easily got them from Karachi Stock Exchange a company’s annual reports are undoubtedlyRead MoreMr Mitchel Lowe1052 Words   |  5 PagesLoNGSTEEPLE and SWOT analysis of Domino’s Pizza Business Functions in Context Mitchel Lowe The University of Winchester LoNGSTEEPLE and SWOT analysis of Domino’s Pizza Business Functions in Context Mitchel Lowe Table of Contents Abstract; 1 Introduction: 3 Background on Domino’s Pizza: 3 Background Of the Fast Food Restaurant Industry and Current Climate: 3 LoNGSTEEPLE Analysis: 3 Analysis of Domino’s Pizza using LoNGSTEEPLE: 4 SWOT Analysis: 4 Analysis of Domino’s PizzaRead MoreSwot Analysis : M S991 Words   |  4 PagesHaving the ability to make decisions based on the information that is received by using management tools such as SWOT and PEST allows managers to inform decisions regarding business strategies. This essay will discuss the usefulness and limitations of SWOT and PEST analysis in relation to Marks Spencers and how managers may overcome any limitations and improve management decisions. MS is an international company that was founded in 1884. MS has a range of products and services for their customersRead MoreOxfam : Non Commercial Organisation1218 Words   |  5 Pagesknown by opening their first regular shop in 1948.Goal of this project is recognize the main stakeholders of the company and what are their key interest.Moreover, the project will contain SWOT analysis on the company with analysis on potential market, market size and other factors. Company’s stakeholders Analysis: The company important stakeholders are staff and volunteers, government, customers, supports (donor) and environment.First of all, staff and volunteers are concerned to raise the shop salesRead MoreProject Report on Vodafone1093 Words   |  4 PagesContents:- 1. I - The Introduction II - The Report: Vodafone. III - The Report: Vittorio Colao, CEO Of Vodafone. IV - Conclusion V - References â€Æ' Report Vodafone:- Introduction 2. Vodafone is a British multinational telecommunication Company. It is one of the oldest, largestRead MoreSwot Analysis Table. Strengthsweaknesses. †¢Quality Teachers779 Words   |  4 PagesSWOT ANALYSIS TABLE Strengths Weaknesses †¢ Quality teachers and school leaders †¢ High expectations for students †¢ Teacher motivation †¢ Rigorous teaching †¢ Strong relationship with central office †¢ Flexible †¢ Anticipating and preparing for future challenges †¢ Technology †¢ Communication †¢ Parental involvement †¢ Achievement gaps among student sub-groups. †¢ Lack of instructional programs beyond the academic opportunities for non†college bound students †¢ Reading and math scores needs improvement Opportunities

Wednesday, May 6, 2020

Nothing to Envy Book Review Essay - 3019 Words

Nothing to Envy 2/15/11 Nothing to Envy by Barbara Demick follows the lives of six North Koreans who have experienced a great deal of hardship and turmoil living under one of the most notorious communist regimes. Throughout the years these North Koreans lived through the death of their great Kim Il-Sung, the rise to power of his successor Kim Jong-Il, and the horrific famine that has left many in despair. Although North Korea is constantly in the news globally it is surprising to realize little is known about the country itself. Communist dictatorship has shut out the North part of the Korean peninsula from the outside world and has ruled with an iron fist. In the years following WWII Kim Il-Sung and†¦show more content†¦The family was considered to be part of the lower class system because Tae-woo is of South Korean origin. After he fought in the war he was taken as a POW in what was now part of North Korea and had to assimilate in the communist country. This meant he was sent to work in the mines and would never be able to achieve any higher ranking. This unfortunately was also the case for anyone related to Tae-woo, especially his children. No matter how hard they would study and work, they were to meet the same disappointment their father had faced. â€Å"Your song-bun, as the rating was called, took into account the backgrounds of your parents, grandparents, and even second cousins â€Å"(26). Even ordinary citizens were subjected to invasive screening in order to rank their political trustworthiness. Mi-ran began an innocent relationship with a young man named Jun-sang, who was a few years older than her. Although, Jun-sang came from a good family and was in turn in a higher class, he was intrigued by Mi-ran. They would often walk in the dark of the night, since there was rarely electricity, they were able to do so inconspicuously. She worked hard for her education and was even accepted into a teaching school. She grew tired of the small emaciated children she w ould see everyday. Children would many times come to school without any food and would ultimately stop coming to class. She did not like to think of reasons why they would not be in classShow MoreRelatedNothing From The Korean War On North Korea1399 Words   |  6 Pages Book Review Nothing to Envy: Ordinary lives in North Korea The novel,Nothing to Envy: Ordinary lives in North Korea, tells the stories of six North Korean citizens from Chongjin, third largest city in Democratic People s Republic of Korea. After the Korean War in the 60th, the aid from Communist China and Soviet Union caused industrial growth in North Korea. During this time the daughter of a South Korean Prisoner of War described the hardships she faces as a citizen with tainted blood. TheRead MoreSelf-Determination in Memoirs of a Geisha Essay1344 Words   |  6 PagesSelf-Determination in The Memoirs of a Geisha Memoirs of a Geisha tells the story of a young girl, Chiyo, who transcends her fishing-village roots to become one of Japans most appreciated geishas. Its a story which brings much life into the characters of the book, using many different climaxes as well as conflicts to show the many different relationship of the characters. Chiyo goes through many hardships throughout the reading, but once finally accepting her fate, she is finally determined to become the successfulRead MoreEssay on Changing Conceptions About What Emotion is939 Words   |  4 Pagestheir theories. Aristotle, who lived in the 4th century BC (384ï ½Å¾322), might be called the first cognitive theorist of emotion in western culture. He used the word â€Å"passion†for emotion and said that emotion includes appetite, anger, fear, confidence, envy, joy, love, hate, longing, emulation, pity and some other more complicated emotional states related to happiness and pain.. While he believed that our soul is made up of emotion, potential and quality, he thought that emotion is the non-rational partRead MoreA Good Man Is Hard to Find OConner Essay example1745 Words   |  7 Pagesno ending and no beginning but Flannery, in her style of literature starts off with a point and ends with a bang! She isnt afraid to tackle the issue of death nor is she afraid to discuss God and virtues. I really appreciate her because she fears nothing in her writing. OConner was a southern gothic American writer born into an Orthodox Christian family in the state of Georgia. At the age of 12 she moved to her mothers birth place, Milledgeville where most of her experiences came from and whereRead MorePsychoanalytic Ideas And Shakespeare By Inge Wise And Maggie Mills1420 Words   |  6 Pagesis on the book Psychoanalytic Ideas and Shakespeare, edited by Inge Wise and Maggie Mills, Published by Karnac Books , London , 2006 ; research and descriptions by numerous authors who wrote on the writing works of Shakespeare, Freud’s work on the psychological works on Shakespeare in general are used throughout the book . The authors focus on psychopathic fiction characters in six plays Hamlet, Macbeth, twilight nights, King Lear, and the Tempest. The book when you read the reviews and the inductionRead MoreNegative Consumer Behavior What is negative consumer behavior and what are the characteristics of a bad customer? How can managers address this issue to ensure success?1490 Words   |  6 PagesNegative Consumer Behavior To fully understand what negative consumer behavior is and what makes a bad customer, we first have to understand what consumer behavior is. In their book, Consumer Behavior: Concepts and Strategies, Berkman and Gilson (1981) say that the American Cultural System, which is made of values and artifacts, strongly influences consumer activity in the United States. In the twentieth century, American Culture reflected a distinct consumption ethic based upon affluenceRead MoreEssay about Annabel Lee, Edgar Allan Poe1009 Words   |  5 Pagesarouses a sense of kinship when read, and takes the reader into his world. Edgar Allan Poe has been deemed the, â€Å"Father of Mystery† by many of his admirers (Kelleghan 520). He became one of the most controversial authors of his time. In Kennedy’s book, â€Å"A Historical Guide to Edgar Allan Poe† he states, â€Å"Despite persisting disagreement about Edgar Allan Poes literary achievement, no American writer of the antebellum period enjoys greater current popularity and recognizability† (3). Poe’s life couldRead MoreThe Outsiders By S. E. Hinton1718 Words   |  7 PagesMajor Work Review Guide Title: The Outsiders Author: S.E. Hinton Published: 1967 by Viking Press Significant characters and brief statement of function in the work: Name: Function: 1. Pony boy Curtis- The narrator of the story. Ponyboy’s love for literature and academics make him different from the rest of the gang. He’s also the youngest. Because his parents died in a car accident, Ponyboy lives with his brothers. His oldest brother accuses him of lacking common sense but, ponyboy is a reliableRead More Chaucers The Canterbury Tales: The Parson’s Tale Essay2219 Words   |  9 Pagesinformation from the sinner (20-21). The cardinal sins were used as a sort of sieve, allowing for classification of specific sin. Interestingly enough, Morton Bloomfield notes that early Celtic manuals list Cassian’s eight chief sins (pride, envy, wrath, lechery, gluttony, greed, tristitia, and vainglory -- the last would be merged with pride, and tristitia would eventually be termed accidia by Gregory the Great. The Gregorian seven have formed our notion of the â€Å"seven deadly sins.†)(67-72)Read MoreNature Vs. Nurture : Nature And Nurture1794 Words   |  8 Pagesisolation by being strapped to a potty chair, where she stayed indefinitely, whether she was eating, sleeping or doing nothing at all. Genie had just entered her teenage years, but could barely walk, talk or otherwise behave normally. Genie was forced to be alone all the time, and had nothing to do, or anyone to talk to. A social worker discovered her, still in diapers. In the review of the book, Letters, the author wrote: Genie was hospit alized in November 1970 at the age of 13, not because she did not speak

Business Analysis Business Analytics Essay - 1990 Words

Business Analytics is focused on the latest business intelligence tools, technology and trends for business executives who plan, build, and use business intelligence products and solutions. Today great business intelligence and analytic technologies are allowing big companies to go big, go fast, go deep, go cheap and go mobile with business data. Business Analytics is used to analyze large amounts of data by applying statistical tools and techniques in order to generate business insights. The key to this ability is this company’s closed loop of testing, learning, and acting on new opportunities. In this company, Analytics has become such a focus that all analytical people were recently combined into one organizational unit. Thus the extensive use of analytical and business performance has transformed their ability to compete on analytics into a key point of differentiation and lasting competitive advantage. This company had to come up with viability of potential customers in the market, product research, and marketing campaigns and lead generation. All the activities expected of Siemens Healthcare company were attained through the help of analytics. Analysis I had interned in other companies in the past, but none the companies had an elaborate analytical driven marketing campaigns that were result oriented. The very concept of market analytics was new to me. The process enabled the project managers to evaluate the success of the marketing implementation through theShow MoreRelatedBusiness Analysis : Business Analytics Essay944 Words   |  4 PagesBusiness Analytics Business Analytics, is a system that use various techniques and processes to gather information to used be used to make business decisions. The data is used to answer a question. Often this is used in marketing. It helps to take away some of the â€Å"guess work† out of who market will target. This process has been credited with increasing the ability of organizations to be more competitive. Just as important as collecting data is the ability to interpret and apply the data. EssentialRead MoreBusiness Analysis : Business Analytics828 Words   |  4 PagesAbout Business Analytics Business Analytics is a comprehensive method used by businesses deploying sophisticated tools to access past, vast and complex information and then use the acquired data and information to better analyse the organisation and equip its managers with the ability to make a well informed business decision. (http://sydney.edu.au/business/business_analytics Name: Business Analytics Website Name: University of Sydney Year 2015) The Discipline of Business Analytics comprises of aRead MoreBusiness Analysis : Business Intelligence And Analytics1545 Words   |  7 PagesToday’s business environment is increasingly complex and dynamic and organizations must adapt to these changes in order to remain competitive. As a result, organizations must continually realign their operations to meet these business environment pressures and challenges by being as responsive as possible to both their customers and competitors. One such tool that organizations and businesses can enlist in order to build stronger capabilities, improve performance, undertake better decision makingRead MoreAnalysis Of Tencent : A Chinese Investment Company Established By Huateng Ma And Zhidong Zhang1743 Words   |  7 PagesInternet service users in China. The position of Tencent to competing on analytics is to use analytics to ensure the leader position above Chinese Internet companies. Also, it actually has the ability to compete with other companies on analytics. As one of biggest company in the world, Tencent has the great ability to get the data through their social media platforms. Business has different degrees including reporting and analytics. By the data they got, Tencent not only can get what is happening withRead MoreThe Association For Manufacturing Technology1728 Words   |  7 Pagesof our members’ businesses. As that active partner, AMT facilitates networking, collaboration, technology awareness, business opportunities, and productivity solutions.†[1] One of the main areas AMT invests a considerable amount of time and money towards satisfying its mission, is by leveraging business intelligence for internal operational improvement in addition to offering business intelligence products and services. Creating Competitive Advantage Within the Four Pillars Over the course of its entireRead MoreThe Year I Won Chess Nationals817 Words   |  4 Pageshelped me make the right moves. Years later, working at a management consulting startup as a business analyst, I helped clients, ranging fledgling startups to industry leaders, make well-informed decisions by providing them with data-backed business intelligence. Today, with over three years’ experience in Management and IT consulting I feel prepared to make the most out of a Master’s program in business analytics that would help me realize the power that data and the value that could be extracted fromRead MoreBrief Overview of Business Intelligence and How Walmart Uses It858 Words   |  4 PagesBrief Overview of Business Intelligence and How Walmart Uses It Walmart is the biggest retailer in the world and handles more than one million customer transactions every hour and generates more than 2.5 petabytes of data storage (Venkatraman amp; Brooks, 2012). To put this into perspective, this data is equivalent to 167 times the number of books in America’s Library of Congress (Venkatraman amp; Brooks, 2012). So how can Wal-Mart use this massive amount of data and what useful informationRead MoreHow Organizations Are Competing On Analytics Essay1785 Words   |  8 PagesOrganizations are competing on analytics not just because they can- business today is awash in data and data crunchers- but also because they should. At a time when firms in many industries offer similar products and services, and use comparable technologies, businesses are among the last remaining points of differentiation. And analytics competitors wring every last drop of value from those processes. So, like other companies, they know what products their customers want, the prices they are willingRead MoreBusiness Analysis : Large Amounts Of Data Essay2189 Words   |  9 PagesBusiness analysis is a significant aspect of any business and company. This is mainly because change is the only constant thing that needs to be constantly dealt with. Change can happen in both your target market and in the industry your business or company belongs to, and for your business to survive and succeed despite these changes, proper business analysis must be conducted at the right time. In such a cutthroat business environment, business analysis is essential in order to maintain competitivenessRead MoreSample Resume : Business Information1244 Words   |  5 PagesUniversity. With the use of business information resources, the information revolution is here - It creates a competitive advantage by providing companies with new ways to outperform their competitors. Knowledge is power and business information companies provide that. The process of involving in t he consolidation, analysis and communication of business information to assist the business decision makings captivates me. Globalization is one of the toughest challenges faced by the business today. The problems

Human Resource Management & Leadership-Free-Samples for Students

Questions: 1 Describe how this Initiative would Impact the Induction Program for new frontline Managers joining Ambulance Service NSW. 2 The focus of this Program has been on Managers. What learning and development now needs to be undertaken for the following positions to further support the change in focus for the Organisation? Answers: 1.This initiative would impact the induction program for the new frontline manages. The new things to be incorporated are: The frontline managers should be engaged early in the learning culture Personal analysis- In order to determine the importance of the Ambulance Management Qualification and its relevance it is required to undertake a personal analysis Evaluation- to determine the effectiveness, the frontline managers must be tested before and after the initiative being taken Performance analysis-the results of performance after the initiative should be analysed to identify the areas of improvement. It may include modifying the 12 day programme (O'Meara 2015) 2.Learning and development needs that are to be undertaken for- Frontline operational staff and Customer service staff- microanalysis and personal analysis of these staff is required because they do not participate in AMQ. Instead, they also manage staff Moreover, the macro analysis of the organisation has already been conducted but the task analysis was not conducted. Further, based on this analysis, there is need of development of tailored LD. It may include online learning to increase opportunities, leadership training, executive development and cross cultural training (Francis and Mazany 2013). References Francis, S.D. and Mazany, P.C., 2013. Developing elements of a learning organization in a metropolitan ambulance service: strategy, team development and continuous improvement.Health manpower management. O'Meara, P., 2015. Searching for paramedic academics: vital for our future, but nowhere to be seen!.Australasian Journal of Paramedicine,4(4).

Tuesday, May 5, 2020

Clinicopathological Correlates of Adrenal †Free Samples to Students

Question: Discuss about the Clinicopathological Correlates of Adrenal. Answer: Introduction: Elevated levels of cortisol hormone are mainly responsible for the occurrence of Cushing syndrome. Cortisol is mainly produced by adrenal glands in the body. Cortisol performs important functions in the body like regulation of blood pressure and normal functioning of cardiovascular system. Cortisol is also helpful in responding to stress and metabolizing carbohydrates, proteins and fats in the usable energy. However, elevated levels of cortisol, disrupt these physiological processes and lead to development of Cushing syndrome. Cortisol levels in MV might increase due to high levels of stress, malnutrition, depression and high levels of emotional stress. Cortisol levels in a person can also increase due to athletic training, alcoholism and panic disorders. High doses of anti-inflammatory medications like corticosteroids might increase cortisol levels. Pituitary gland releases more adrenocorticotropic (ACTH) hormone in pituitary gland tumor. This increase in the adrenocorticotroic horm one is known as Cushings disease. Adrenal gland abnormality or tumor might cuase Cushings syndrome. Even though70 80 % cases of the Cushing's syndrome occur due to excessive secretion of ACTH from the pituitary adenomas, it is evident that only 10 15 % pituitary adenomas secret excessive ACTH. Even though approximately 10 % cases of the Cushing's syndrome occur due to excessive secretion of cortisol from the adrenal adenomas, it is evident that only 6 % adrenal adenomas secret excessive cortisol. However, exact aetiology of excessive secretion of ACTH from pituitary adenomas and cortisol secretion from adrenal adenomas has not been well established. Genetic studies established that mutation in the ubiquitin-specific protease 8 is responsible for Cushing's disease 1,2. Difference between Cushings syndrome and Cushings disease: Tumor in the adrenal gland produces more amount of cortisol. This leads to the development of Cushings syndrome. Cushings syndrome can also be developed due to tumor in the pituitary gland. Cushings syndrome is the group of symptoms in which cortisol levels remains elevated for the longer duration. Tumor in the pituitary gland produces more amount of ACTH. This ACTH stimulates more secretion of cortisol from the adrenal gland. This type of Cushings syndrome is called as Cushings disease. Tumors produced by ACTH can be produced anywhere in the body and these are termed as ectopic tumors. Long term steroid administration is one of the causes of Cushings syndrome. Cushings disease may occur due to the endogenous factors like self-overproduction of cortisol by the body. Endogenous over-production of cortisol may occur due to pituitary tumor (Cushings disease), adrenal tumor and ectopic tumors3. Hypothalamus is the part of brain below which pituitary gland is present. Corticotropin-releasing hormone (CRH) is secreted by paraventricular nucleus (PVN) of the hypothalamus. CRH stimulates pituitary gland to secret ACTH. ACTH gets transported through blood and as result adrenal gland gets stimulated to secret cortisol. Zona fasciculata is the region of cortex of adrenal gland which is responsible for the secretion of cortisol. Corticosteroid hormones are under the control of hypothalamus-pituitary-adrenal axis. Corticosteroids exhibit most prominent metabolic activity during the postprandial period. During this period, these hormones behave as contra-insular hormones. Hence, it provides substrates for oxidative metabolism and stimulate lipolysis and proteolysis. This results in the release of fatty acids and amino acids which induce glucose production by stimulating gluconeogenesis and inhibiting glycogen synthesis. Elevated levels of cortisol are responsible for the negative fee dback which is responsible for the reduced secretion of ACTH. Pathophysiology: In all types of etiologies of Cushing syndrome, there are raised levels of cortisol. Cortisol secreting adenoma in the cortex of adrenal gland occurs in Cushings syndrome. This adenoma of cortex of adrenal gland might be of primary hypercortisolism or hypercorticism types. Cushings syndrome due to elevated levels of ACTH is known as ectopic Cushing syndrome. Patients with severe hypercortisolism are associated with the phenotypes like glucose intolerance, dyslipidaemia, metabolic bone disease, and abnormal weight gain. On the other hand patients with mild or moderate hypercortisolism are rarely associated with glucose intolerance, dyslipidaemia, metabolic bone disease, and abnormal weight gain. Hence, it would be difficult to differentiate these patients from other patients with metabolic syndrome. There is presentation of striae, supraclavicular fat pads, and proximal muscle weakness in patients with increased hypercortisolism6. Elevated levels of corticosteroids results in the augm ented production of glucose at the level of liver and skeletal muscle. In liver corticosteroids increase levels of glucose by stimulating gluconeogenesis and inhibiting insulin sensitivity. Corticosteroids stimulate gluconeogenesis by acting on different genes responsible for glucose metabolism. Corticosteroids reduce insulin sensitivity by exerting antagonistic effect on metabolic action of insulin which is most important hormone required for suppression of glucose production7,8. Corticosteroids decrease expression and phosphorylation of insulin receptor substrate (IRS)-1, phosphatidylinositol-3kinase (PI3K) and protein kinase B (PKB/AKT). As a result, there is decrease in migration of glucose transporter GLUT4 to the cell surface which results in the reduction of glucose uptake. It also leads to decrease of glycogen synthase kinase (GSK)-3 phosphorylation and results in the decrease of glycogen synthesis. In skeletal muscles, corticosteroids increase insulin resistance which results in the decreased glucose uptake and prevention of glycogen synthesis. Corticosteroids exhibit effect on insulin resistance by directly acting on the insulin receptor or alteration in the insulin function by altering lipid and protein metabolism9,10. Corticosteroids also play prominent role in the regulating adipose tissue differentiation, distribution and metabolism. Corticosteroids can stimulate differentiation of pre-adipocytes in adipocytes. Increased adipocytes are associated with raised body fat mass. Corticosteroid specifically act on visceral fat and not on the peripheral fat. Hence, corticosteroids are associated with central obesity in Cushings syndrome. Corticosteroids also play role in the release of hormone like adipokine which is responsible for the development of insulin resistance. Co-occurrence of insulin resistance and increased visceral fat can lead to the development of metabolic syndrome which is associated with impairment in the glucose metabolism. Metabolic syndrome comprises of visceral obesity, diabetes mellitus, and dyslipidemia. Effect of corticosteroids on the pancreatic beta cells result in the decreased insulin secretion. Corticosteroids exhibit effect on insulin secretion in dose dependent and time dependent manner. Corticosteroid exhibit effect on different steps of insulin secretion like glucose uptake, glucose utilization and calcium fluxes and exocytosis of granules containing insulin. Glucose transporter GLUT2 and glucokinase expression gets reduced due to corticosteroids11,12. Corticosteroids can change AMP-activated protein kinase (AMPK) activity in tissue specific manner. Suppression of AMPK is proportional to hypercortisolism. Due to tissue specific activities, AMPK increases appetite, visceral obesity and dyslipidemia. Upon activation, AMPK plays key role in glycolysis and fatty acid synthesis which produces ATP. Due to hormone-sensitive lipase (HSL), there is increased level of lipids form adipose tissue which lead to development of adipocytes. 11 - hydroxysteroid dehydrogenase type 1 (11 H SD1) is responsible for the activation of cortisol from the inactive cortisone. 11 H SD1 overexpressed in mature adipocytes in conditions like hepatic steatosis and there is increased levels of cholesterol and triglycerides. 11 H SD1 is also associated with insulin resistance. Cardiovascular complications associated with corticosteroids include systemic arterial hypertension, atherosclerosis, and thromboembolism. It has been established that elevated levels of corticosteroid can lead to the increase in renin-angiotensin system, stimulated sympathetic nervous system and endothelin system. It also leads to reduced nitric oxide (NO) synthesis and kallikrein-kinin system. Patients of Cushings syndrome are associated with irreversible arterial stiffness. Endothelin, homocysteine, vascular endothelial factor, adrenomedulin, and cell adhesion molecules are the markers of endothelial dysfunction and are responsible for vascular endothelial and smooth muscle proliferation and fibrosis around vessels and consequently development of atherosclerosis plaques. In subclinical Cushings syndrome both systolic and diastolic hypertension can occur. Blood pressure can elevate in patients with Cushings syndrome due to ACTH stimulated cortisol level15,16. Corticosteroids also p roduces immunosuppression and neuropsychiatric complications. Ectopic ACTH production lead to Cushings syndrome and neurocognitive impairment. Neuropsychiatric disorders associated with Cushings syndrome are major depression, mania, anxiety, and cognitive impairment17. Bone complications associated with corticosteroids include osteoporosis and osteoarthritis. Osteoporosis may occur in patients with Cushings syndrome due to increased bone reabsorption, decreased bone formation, reduced intestinal calcium absorption and increased urinary calcium excretion18. Molecular Pathology: Adrenocortical carcinomas are associated with clinical hypercortisolism and androgen overproduction. Elevated levels of urinary metabolites of androgens or glucocorticoid precursors are evident in the adrenocortical carcinomas. It reflects reduced activity of steroidogenic enzymes. Bilateral macronodular adrenal hyperplasia (BMAH) is seldom connected with MEN1, familial adenomatous polyposis, and fumarate hydratase gene mutations. Bilateral adrenal hyperplasias are presented as in the form of nodule diameter greater than 1 cm (macronodular) or less than 1 cm (micronodular). Patients with Cushings syndrome possesses ARMC5 gene mutations and associated with subclinical BMAH. In addition to the ARMC5 gene mutation, there is occurrence of mutations in histone H3 lysine 79 methyltransferase gene (DOTL1), in a histone deacetylase gene (HDAC9), or in a prune homologue 2 gene (PRUNE2) in BMAH19,20. Molecular genetic abnormalities are helpful in the identifying causes of the Cushings syndrome. Glucocorticoid receptor gene mutation, dysfunction of proteins related to glucocorticoid-receptor function (Brg1 and HDAC2), and TP53-inactivating defects are responsible for the occurrence of Cushings syndrome. Overexpression of testicular orphan receptor 4 (TR4),30 a nuclear receptor with unknown ligand, the pituitary transforming gene (PTTG),31 and epidermal growth factor receptor are responsible for occurrence of Cushings syndrome. Overexpression of these genes are useful in identifying causal relationship and establishing therapeutic roles. Somatic mutations in the ubiquitin speci?c peptidase 8 gene (USP8) established role of epidermal growth factor receptor in Cushings syndrome. USP8 inactivation produces augmented epidermal growth factor receptor deubiquitination which leads to impairment in its down regulation and increased growth factor signalling and pro-opiomelanocortin (POMC) a nd ACTH synthesis. Mutations in the cAMP-dependent or -catenin signalling pathways are expresses in the adrenal adenomas. Mutations of GNAS (encoding Gs, which activates adenylate cyclase) are reported in cortisol secreting adenomas and -catenin (CTNNB1) mutations in cortisol-secreting adenomas. Protein kinase A (PRKACA) mutations are reported in adenomas of Cushings syndrome. Phosphodiesterase 11A (PDE11A) or phosphodiesterase 8B (PDE8B) genetic variants are responsible for adrenal adenomas21. Most of the clinical features of Cushings syndrome like body weight gain and blood pressure are common. Hence, it would be difficult to make exact diagnosis of Cushings syndrome. Hence, laboratory tests need to be performed for the diagnosis of Cushings syndrome. These tests would also be helpful in identifying Cushing disease which mainly occurs due to tumor of pituitary gland. Dexamethasone suppression test and 24-hour urinary and salivary measurement for cortisol are useful for the confirmation of Cushings syndrome. Dexamethasone suppression test involves frequent administration of dexamethasone and continuous monitoring of cortisol and ACTH levels. In this test, if body is monitoring cortisol, there would be decrease in the cortisol level. However, in cases of Cushings syndrome, there would be increase in the cortisol level. This test is not always useful because other illness or condition may produce high level of cortisol. This condition is called as pseudo-Cushings states. Doc tors need to treat pseudo-Cushings states like depression. Post treatment, if there is no reduction in cortisol along with other physical worsening, Cushings syndrome would be confirmed. ACTH measurement in the blood can be useful in differentiating Cushings syndrome and Cushings disease. Blood ACTH levels would be less in cases of Cushings syndrome, however it would be normal or higher in cases of Cushings disease. This is because, blood ACTH levels would be less in patients with adrenal origin Cushings syndrome as compared to the other origin of Cushings syndrome. ACTH producing tumor from the pituitary origin can be differentiated from the other parts of origin by using inferior petrosal sinus sampling, or IPSS. In this test, small plastic tube need to be inserted in the right and left veins in the groin and attach them to the veins near the pituitary gland. Blood should be collected form these veins and other locations far from the pituitary. During this procedure, medications which increase ACTH levels from the pituitary need to be injected. ACTH levels produced near pituitary and far from the pituitary need to be measured to assess tumors produced by pituitary origin. Inferior petrosal sinus sampling (IPSS) is more reliable as compared to the dexamethasone suppression test. Magnetic resonance imaging (MRI) can also be used as a diagnostic tool for Cushings syndrome. In this test, contrast is useful for showing up tumor in the MRI scan. Identification of the definitive tumor along with positive dexamethasone suppression test would be useful in diagnosis of Cushings disease. In such cases, there is no requirement of IPSS test. In few healthy people, there may be abnormal area on the pituitary, which might resemble tumor in MRI, hence abnormality doesnt reflect occurrence of Cushings disease. In few cases, tumor may be too small to detect using MRI. Hence, absence of tumor should not exclude Cushings syndrome. Sodium and potassium levels can be increased in patients with Cushings syndrome, hence assessment of electrolyte balance can be used as a diagnostic tool23. Treatment and management: Main aim of the treatment of Cushings syndrome should be reduction in the level of cortisol. Treatment of Cushings syndrome may vary based on the cause of the disease. Corticosteroid medication use should be reduced. Dose of the corticosteroid should be reduced. However, reduced dose of corticosteroid should be useful in the management of chronic inflammatory disease. Non-corticosteroids drugs can be administered along with corticosteroids to reduce dose of corticosteroids. Use of corticosteroids should not be stopped abruptly because it may lead to decrease in cortisol levels. In patients with existence of tumor, surgery should be performed to remove tumor. Pituitary tumors can be removed by performing surgery through nose and neurosurgeon can perform this surgery. Adrenal gland tumors can be removed by standard surgical procedure and using minimally invasive surgical technique. After the completion of the surgery, cortisol replacement medications should be provided to the patients to maintain normal levels of cortisol. Cortisol replacement medications usually takes long duration to maintain normal level of cortisol. Radiation therapy should be provided to the patients, in whom surgeon cant remove tumor completely. Hence, in such cases radiation therapy should be used as an adjuvant therapy along with surgery. Radiation therapy should be used in patients in whom surgery can not be performed. Radiation should be given in little doses for a duration of 6 weeks. Stereotactic radiosurgery, which is also called as Gamma Knife surgery can also be used, in which large single dose of radiation should be given to tumor part with minimal exposure to the surrounding area. Medications to control cortisol levels should be administered to patients, whom are very sick and surgery can not be performed in such patients24. Ketoconazole, mitotane and metyrapone can be used to reduce excessive production of cortisol from the adrenal gland. It is evident that, Ketoconazole can reduce plasma cortisone, however it can not reduce plasma ACTH. Metyrapone exhibits its action by inhibiting 11-hydroxylase. Due to use of metyrapone, there may be increase in ACTH levels relative to the decrease in the cortisol levels. This may result in the stimulation of the adrenal androgen and increased mineralocorticoid production. Mifepristone is useful in the Cushings syndrome patients with diabetes and glucose intolerance. Mitotane exhibits its action by inhibiting 11-hydroxylase, 18-hydroxylase, 3-hydroxy-lase, hydroxysteroid dehydrogenase, and several cholesterol side chain cleavage enzymes. Mitotane exhibits adrenolytic action by binding its metabolite to the macromolecules in adrenal cortical cell mitochondria. This results in the cell destruction and cellular necrosis. Mifepristone does not reduce cortisol level; howev er it blocks action of cortisol on tissues. Pasireotide is useful in the Cushings disease because it reduces the ACTH secretion from pituitary tumor. This medication should be administered twice daily, if surgery can not be performed or in cases of unsuccessful surgery. If none of the treatment works, bilateral adrenalectomy should be performed. In bilateral adrenalectomy, there would be surgical removal of adrenal gland. This surgical intervention is useful in reducing excess levels of cortisol, however such patients require life-long cortisol replacement medications. Newer compounds like CDK2/cyclin inhibitor R-roscovitin (targeting PTTG overexpression) or ge?tinib, the epidermal growth factor receptor-tyrosine kinase inhibitor are responsible for the inhibition of corticotroph tumour growth. Hence, these compounds are helpful in the alleviate clinical and biochemical features of Cushings syndrome. Ge?tinib exhibits effect in Cushings syndrome by decreasing ACTH secretion in USP8-mutated human corticotroph cells26. Patients with Cushings syndrome should take care of their general health. They should take healthy diet and exercise on regular basis. High impact or heavy weight exercise should be avoided by patients with Cushings syndrome because bones might weaken in these patients. More amount of calcium and vitamin D should be administered to strengthen the bones. Patients with Cushings syndrome should quit smoking and avoid consumption of large quantity alcohol. Nurse should advise MV to follow-up regular basis. MV should inform doctor about adverse effects of medications. Nurse should advise MV to keep adequate supply of corticosteroids to avoid shortage. MV and her family members should be aware of evaluating and measuring blood pressure, blood glucose and body weight. Safe environment should be provided to MV because there is possibility of fall due to weak bones. Fall prevention strategies should be provided to MV. MV should wear identification mark for Cushings syndrome, hence other docto rs can identify her as patient. Nurse should encourage MV to verbalize feelings and concerns. MV and family members should adapt to the emotional instability and should cope with mood swings, irritability, and depression. Assurance should be given to MV that, physical changes occurred due to Cushings syndrome can be disappeared if cause of the disease treated. Weight gain and edema can be managed by consuming low carbohydrate and low sodium diet. Conclusion: Excessive exposure to glucorticoids results in mortality and morbidity due to Cushing's syndrome. Genetic and molecular studies established that primary adrenal lesions and ACTH secretion are responsible for the excessive secretion of cortisol. Biochemical and imaging diagnostic studies proved useful in differentiating Cushing's syndrome from Cushing's disease. Radiotherapy, drug therapy and surgical treatment improved management of patients with Cushing's syndrome. Management goals for the patients with Cushing's syndrome should be normal functioning of the hypothalamic-pituitary-adrenal axis, normal functioning of the pituitary gland, and evading of tumour recurrence. References: Duan K, Gomez Hernandez K, Mete O. Clinicopathological correlates of adrenal Cushing's syndrome. J Clin Pathol. 2015; 68(3):175-86. Prague JK, May S, Whitelaw BC. Cushing's syndrome. BMJ. 2013; 346:f945. doi: 10.1136/bmj.f945. Ritzel K, Beuschlein F, Berr C, Osswald A, Reisch N, Bidlingmaier M, Schneider H, Honegger J, Geyer LL, Schopohl J, Reincke M. ACTH after 15 min distinguishes between Cushing's disease and ectopic Cushing's syndrome: a proposal for a short and simple CRH test. Eur J Endocrinol. 2015; 173(2):197-204. Gallo-Payet N, Battista MC. Steroidogenesis adrenal cell signal transduction. Compr Physiol. 2014; 4, 889964. Raff H, Sharma ST, Nieman LK. Physiological basis for the etiology, diagnosis, and treatment of adrenal disorders: Cushings syndrome, adrenal insuf?ciency, and congenital adrenal hyperplasia. Compr Physiol. 2014; 4: 739769. Zografos GN, Perysinakis I, Vassilatou E. Subclinical Cushing's syndrome: current concepts and trends. Hormones (Athens). 2014; 13(3):323-37. Resmini E, Minuto F, Colao A, Ferone D. Secondary diabetes associated with principal endocrinopathies: the impact of new treatment modalities. Acta Diabetol. 2009; 46(8): 595. van Raalte DH, Ouwens DM, Diamant M. Novel insights into glucocorticoid-mediated diabetogenic effects: towards expansion of therapeutic options? Eur J Clin Invest 2009; 3(9): 8193. van Raalte D, Nofrate V, Bunck M, Van Iersel T, Elassaiss Schaap J, Nssander U, Heine R, Mari A, Dokter W, Diamant M. Acute and two-week exposure to prednisolone impair different aspects of beta-cell function in healthy men. Eur J Endocrinol. 2010; 1(62): 729735. Pivonello R1, De Leo M, Vitale P, Cozzolino A, Simeoli C, De Martino MC, Lombardi G, Colao A. Pathophysiology of diabetes mellitus in Cushing's syndrome. Neuroendocrinology. 2010;92(1):77-81. Abraham SB, Rubino D, Sinaii N, Ramsey S, Nieman LK. Cortisol, obesity, and the metabolic syndrome: a cross-sectional study of obese subjects and review of the literature. Obesity (Silver Spring). 2013; 21(1):E105-17. London E, Lodish M, Keil M, Lyssikatos C, de la Luz Sierra M, Nesterova M, Stratakis CA. Not all glucocorticoid-induced obesity is the same: differences in adiposity among various diagnostic groups of Cushing syndrome. Horm Metab Res. 2014;46(12):897-903. Arnaldi G, Scandali VM, Trementino L, Cardinaletti M, Appolloni G, Boscaro M. Pathophysiology of dyslipidemia in Cushing's syndrome. Neuroendocrinology. 2010;92(1):86-90. Ferra F, Korbonits M. Metabolic comorbidities in Cushing's syndrome. Eur J Endocrinol. 2015;173(4):M133-57. Valassi E, Biller BM, Klibanski A, Misra M. Adipokines and cardiovascular risk in Cushing's syndrome. Neuroendocrinology. 2012;95(3):187-206. Luigi Petramala, D'Elia Lorenzo, Gino Iannucci, Antonio Concistr, Laura Zinnamosca, Cristiano Marinelli, Giuseppe De Vincentis, Antonio Ciardi, Giorgio De Toma, and Claudio Letizia. Subclinical Atherosclerosis in Patients with Cushing Syndrome: Evaluation with Carotid Intima-Media Thickness and Ankle-Brachial Index Endocrinol Metab (Seoul). 2015; 30(4): 488493. Starkman MN. Neuropsychiatric findings in Cushing syndrome and exogenous glucocorticoid Administration. Endocrinol Metab Clin North Am. 2013;42(3):477-88. Miklos Toth, Ashley Grossman. Glucocorticoid-induced osteoporosis: lessons from Cushings syndrome. Clinical Endocrinology. 2013; 79, 111. Lib R, Coste J, Guignat L, et al. Aberrant cortisol regulations in bilateral macronodular adrenal hyperplasia: a frequent ?nding in a prospective study of 32 patients with overt or subclinical Cushings syndrome. Eur J Endocrinol. 2010; 163: 12938. Ho? and J, Ho? and LJ, van Koetsveld PM, et al. ACTH-independent macronodular adrenocortical hyperplasia reveals prevalent aberrant in vivo and in vitro responses to hormonal stimuli and coupling of arginine-vasopressin type 1a receptor to 11-hydroxylase. Orphanet J Rare Dis. 2013; 8: 142. Andr Lacroix, Richard A Feelders, Constantine A Stratakis, Lynnette K Nieman. Cushings syndrome. Lancet. 2015; 386: 91327. Judith Lowitz, Margaret F. Keil. Cushing Syndrome: Establishing a Timely Diagnosis. J Pediatr Nurs. 2015; 30(3): 528530. Rajput R. Cushings syndrome An update in diagnosis and management. Journal, Indian Academy of Clinical Medicine. 2013; 14(3-4): 235-41. Barnett R. Cushing's syndrome. Lancet. 2016; 13;388(10045):649 Reincke M, Ritzel K, Owald A, Berr C, Stalla G, Hallfeldt K, Reisch N, Schopohl J, Beuschlein F. A critical reappraisal of bilateral adrenalectomy for ACTH-dependent Cushing's syndrome. Eur J Endocrinol. 2015;173(4):M23-32. Fukuoka H. New potential targets for treatment of Cushing's disease: epithelial growth factor receptor and cyclin-dependent kinases. Pituitary. 2015;18(2):274-8. Ragnarsson O, Johannsson G. Cushing's syndrome: a structured short- and long-term management plan for patients in remission. 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Saturday, April 11, 2020

Essay of Claim of Author

Essay of Claim of AuthorOne of the keys to getting an A in college, after taking a final exam, is knowing how to write a sample essay of claim of the author. If you don't know what you are doing you will waste time and your paper may be rejected. It's really easy to make an essay look like a bad one. I've seen so many that are submitted to colleges that sound terrible.In addition to writing an essay of claim of the author, you must also use your writer's skills and your writing style. Because a very few people know how to write an essay, if they don't use the proper type of language you can get your essay disqualified. Your writing style will show if you know how to use strong words, good grammar, and write with great clarity. You'll need to write an essay that makes the reader think. If you use the same type of language to start your essay that you would use to go into detail about a topic, it will show that you know how to use it to communicate.Make sure you have a different type o f person in mind when you read it. If you are talking about something you learned in school or from a book, you will need to use strong language and make a statement that will make the reader feel something. In your essay of claim of the author, you should use your reader's emotions to make a strong statement. Sometimes an emotional response can make a point clear. A very few will do this, but if you use a lot of words that make no sense, you will lose points on this aspect.Next, be sure you follow the format and paragraph that are used in the school you are going to. These paragraphs and formats are calling norms and will be found in every publication for which you submit your essay. Be sure you follow them and never create any essay of claim of the author that does not follow the norms. Youressay will be rejected if you don't.Get to the point. Many schools require essays to have facts, figures, and statements that are factual. When you read this in an essay of claim of the author, you can become very emotional because it is important that you present facts and figures in a way that will tell the reader something. This part of your essay needs to make the reader do something, and you want to make them feel something by providing them with information.Finally, don't forget to use the article format. You will find articles to be very well-known, and they are perfect for essay of claim of the author. You may get a letter grade, but an essay that uses the article format is much better than an essay that doesn't.Don't let your lack of writing skills ruin the essay of claim of the author that you are submitting. Always remember to use strong language, build your emotions, and follow the norm of the school where you are writing.

Wednesday, April 8, 2020

Caesar Essays - Cleopatra, Julius Caesar, Julio-Claudian Dynasty

Caesar Expository Essay The decisions that one man makes can determine the length of life. Rome has many people that have the characteristics to be great leaders. Antony is a manipulative man, Brutus is an honorable man, and Octavius is a quiet strength. All three men would do an excellent job in leading Rome. Antony is a manipulative man. This is shown throughout the play in several cases, but most prominently at Caesar's funeral. ?I thrice presented him a kingly crown which he did thrice refuse. Was this ambition (III, ii, 96-96). Antony is very cleaver in the way that he presents his case to the people. He uses rhetorical questioning to show the people that Caesar was in fact not ambitious. Antony also played on the people's greed, to influence them to his side. ?I found it in his closet; ?tis his will/and they would go kiss Caesar's dead wounds (III, ii, 129, 132-133). Antony is very smart in the way he does this. He knows how to talk to the people to get them to believe his side of the story and revenge Caesar's death. Likewise, Antony is conniving. He uses this strength by flattering Brutus, and falsely befriending the conspirators into letting him speak at Caesar's funeral. ?I doubt not of your wisdom. Let each man render me his bloody hand.? (III, i, 200-201). Antony presents his c ase in such a way that Brutus and the other conspirators think that he is on their side, when in fact he really is going to turn the common people against them to revenge Caesar's death by creating a war. Furthermore, Brutus is an honorable man giving him the chance to be a great leader. Brutus is an idealist man, who is optimistic about assassinating Caesar. ?Grant that, and then is death a benefit. So are we Caesar's friends (III, i, 115). Brutus believes that with Caesar gone, Rome will greatly benefit. The common people will not be treated like bondsman, and Rome will not have someone who is driven by ambition to take over their country. Additionally, Brutus is also a noble person. Brutus helped in the assassination of Caesar not for personal gain but for the love of Rome. ?Not that I loved Caesar lee, but that I loved Rome more.? (III, ii, 21-22). Brutus is able to satisfy that his motive is pure; that his action is without bitterness and that the assassination of Caesar is for the general good of Rome. Brutus is also rigidly mortal. ?I did send to you For certain sums of gold, which you denied me, For I can raise no money by vile means. By heaven, I had rather coin my heart And drop my blood for drachmas than to wring From the hard hands of peasants their vile trash By any indirection. I did send To you for gold to pay my legions, Which you denied me.? (IV, iii, 78-86) Brutus is distressed with Cassius because he is led to believe that Cassius is accepting bribes, and denying Brutus the proper money to pay his troops. Brutus confronts Cassius and tells him that he was wrong to misuse his power and be so dishonest. Brutus clearly states that he loved Rome more than he loved Caesar, which in turn keeps his motives pure and his reasons for helping in the assassination honorable. Above and beyond, throughout the play Octavius is seen as a silent character, yet shows his strengths in several matters. Octavius is seen to be ill tempered. Though he is a quiet man if challenged he will take action. ?I do not cross you; but I will do so.? (V, I, 21). Octavius has much respect for Antony, however if he is challenged, or forced to do so he will cross Antony. This shows us that Octavius will stand up for himself and what he believes in. In addition, Octavius is respectful. ?Within my tent his bones to-night shall lie.? (V, V, 83). Octavius is referring to Brutus' dead body, when he recites these lines. He states this because he has the utter most respect for Brutus and what he stands for. Octavius believes Brutus is a man of importance and one to be honored, so he is going to honor him properly.

Monday, March 9, 2020

Impossible Nest Pas Français

Impossible N'est Pas Franà §ais The French expression impossible nest pas franà §ais is actually a proverb, equivalent to theres no such thing as cant or simply nothing is impossible. In French, you should never say that something is impossible, because, according to the proverb,  impossible isnt even a French word. Likewise, in English, you should never say that you cant do something because the concept of cant doesnt exist. In other words, nothing is impossible and there isnt anything you cant do. It would make a good motivational poster in either language (if youre into that kind of thing). Expression: Impossible nest pas franà §aisPronunciation: eh(n) puh seebl nay pa fra(n) sayMeaning: Theres no such thing as cantLiteral translation: Impossible isnt FrenchRegister: normal Example Tout le monde mavait dit que cà ©tait impossible  ; moi, je leur ai rà ©pondu qu «Ã‚  impossible nest pas franà §ais  Ã‚ » et puis je lai fait. Everyone told me you cant do that; I told them that theres no such thing as cant and then I did it.

Saturday, February 22, 2020

Dances With Wolves Essay Example | Topics and Well Written Essays - 750 words

Dances With Wolves - Essay Example The mule wagon driver and a fort commander are odd personalities; the fort commander commits suicide after he sends Dunbar to his post, so no one is aware that Dunbar is on his legitimate duty. He mans the post alone after finding it deserted, gradually making friends with nearby Sioux villagers. In yet a different suicide incident, a Sioux lady cuts her wrists mourning her husband but Dunbar stops her. She is a white lady who was raised in the village. She becomes Dunbar’s interpreter and they ultimately fall in love The Sioux, the Pawnee and the white’s are all seen as having a conventional despise and hatred of people of other races. There is a great deal of violence: Indian on Indian, Indian on white, white on Indian, and white on white. The Sioux are humanized by being shown all through their lives; hence the viewers’ sympathy stays with them in their wars against the Pawnee, who are depicted as raiders and warriors (Monroe 167). Dunbar and his interpreter g irlfriend are shown making love while she is technically still mourning her husband. The Sioux are shown in a spectacular filmed buffalo hunting were the whites slaughter a lot of buffalos for just their tongues and skin. On contrary the Sioux could not waste any part of a buffalo, even when using insulated stomachs of the buffalos to cook as vessels to carry fire or as pots to cook, while some whites shoot the buffalos from train for pleasure just to see them fall. The federal soldiers are seen committing cruel acts on animals, and are classified as just plain crude (Hunter 98). Watching this film automatically arouses some Whiteman’s guilt (especially when if you are a white) and makes you more sensitive about treating any human being worthy of respect. When the film was first shown on a TV, some vulgar language were curled, but the out footage of with extra violence was added into it making it a four hour, two night mini-series. John Dunbar, a survivor of the civil war wit h a little knowledge of the American frontier and the plight of the Native Americans who inhabit it, acts as the role model of the film. He is open in different ways of life and he is smart, brave, heroic and loyal. Most the native Americans are shown as committed to their families, protect their way of living, eager to laugh, and live in harmony among themselves, an enormously different picture for this people in many other movies that came before this (Kevin Costner 112). With the Dunbar the only exception the other white soldiers are depicted as arrogant, ignorant and brutal. Intensively violent battles scene between the Native Americans and the white soldiers and between different native tribes are very common in the flow of the movie. Both innocents including children and the participants are shot with guns and or arrows. They are killed with hatchets, knifed, scalped or in furious hand to hand combat. Animal and human blood flows through out. Many animals including dogs, horse s and buffalos are attacked and shown bleeding or dying. On the hand the Indians ravage an innocent group of settlers: white soldiers pummel, beat and ferociously kicks the film hero; they also gleefully attack his beloved wolf for the sport of it. Violence is being used as the main theme of the movie though it does not seem to solve the problem. Indians get a